Generation of Animal Models

We specialize in generating transgenic mice and rats with the traditional method of pronuclear microinjection, as well as using lentiviral vectors. LAM assures SPF (Specific Pathogen Free) status of created transgenic animals. Additionally we offer the  cryopreservation,  embriotransfer, and  genotyping  service.

Embriotransfer

Rederivation is a service of converting valuable transgenic lines into Specific Pathogen Free (SPF) status.

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In vitro fertilization

In vitro fertilization is a method used for recovery of mice line from cryopreserved sperm . It may also be used as a method to overcome male fertility problems.

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Genotyping

LAM offers the genotyping service. You should deliver to us tail/ear tissue fragments, PCR primers and reaction condition.

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Transgenic Animals Technology Services

All experiments concerning generation of genetically modified models are performed in the Nencki Institute in Transgenisation unit of Nencki Institute, currently being the part of the Laboratory of Animal Models. 

 

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Cryopreservation

Cryopreservation is cost and time saving method enabling preservation of valuable transgenic lines that are not currently in use.

Read more: Cryopreservation