We are specialized in generating transgenic mice and rats with the traditional method of pronuclear microinjection, as well as using lentiviral vectors. LAM assures SPF (Specific Pathogen Free) status of generated transgenic animals. Additionally we offer the cryopreservation, embriotransfer and genotyping service.
Genotyping
LAM offers the genotyping service. You should deliver to us tail/ear tissue fragments, PCR primers and reaction condition.
In vitro fertilization is a method used for recovery of mice line from cryopreserved sperm . It may also be used as a method to overcome male fertility problems.
All experiments concerning generation of genetically modified models are performed in the Nencki Institute in Transgenisation unit of Nencki Institute, currently being the part of the Laboratory of Animal Models.